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Joshua Gray, Ph.D.

Professor, Section Chief, Chemistry Department of Science

Joshua GrayPROF Gray’s research is focused in two areas. The first investigates the inhibition of microbial growth in the renewable fuel biodiesel. Funded by the Technical Corrosion Collaboration of the Department of Defense, this work analyzes the biology of fungal and bacterial growth at the oil/water interface and the use of novel microbial biocides to prevent their growth and prolong the shelf-life of biodiesel fuels. The second research project investigates the interplay of oxidative stress and metabolism in the nematode worm C. elegans (described below).

PROF Gray also specializes in inclusive, evidence-based teaching practices, including Process Oriented Guided Inquiry Learning (POGIL), Classroom Undergraduate Research Experience laboratories (CUREs), and the Vision and Change model of undergraduate education reform as it applies to Toxicology. For example, biochemistry laboratory is taught as a CURE using C. elegans, a nematode worm commonly used as a model organism for toxicology. This worm is an ideal animal for studying biochemistry due to its fast reproduction rate, inexpensive culturing cost, and the availability of a large number of genetic mutants. Students begin the course by learning about the C. elegans system, including culturing methods and a variety of toxicity assays investigating responses to behavior (such as touch, and chemotaxis), survival, and gene expression using real time quantitative RT-PCR. After the first six weeks of training, students choose an authentic research project to investigate, designing their own research experiments and presenting their findings to their classmates. The semester culminates in a presentation of findings to their peers, describing their findings and discussing their troubleshooting of experiments along the way.

Education

  • B.S. Biochemistry and Molecular Biology, 1998, Pennsylvania State University
  • Ph.D. Pathobiology, 2004, Pennsylvania State University

Courses Taught

  • General Chemistry 1 and 2
  • Toxicology
  • Biochemistry
  • Microbiology
  • Science of Terrorism

Selected Publications and Presentations

  • Gray J.P., Curran C.P., Fitsanakis V.A., Ray S.D., Stine K.E., and Eidemiller B.J. 2019. Society of Toxicology Develops Learning Framework for Undergraduate Toxicology Courses Following the Vision and Change Core Concepts Model. Toxicol Sci. epub ahead of print. DOI: https://doi.org/10.1093/toxsci/kfz090
  • Sanders R.W., Crettol G.L., Brown J.D., Plummer P.T., Schendorf T.M., Oliphant A., Swithenbank S.B., Ferrante R.F., and Gray J.P. 2018. Teaching Electrochemistry in the General Chemistry Laboratory through Corrosion Exercises. J Chem Ed. 95(5): 842-846. DOI: https://doi.org/10.1021/acs.jchemed.7b00416
  • Heart E.A., Karandrea S., Liang X., Balke M.E., Beringer P.A., Bobczynski E.M., Burgos Z-B D., Richardson T., and Gray J.P. 2016. Mechanisms of Doxorobucin Toxicology in Pancreatic β-Cells. Toxicol Sci 152(2): 395-405. DOI: https://doi.org/10.1093/toxsci/kfw096

Honors

  • Undergraduate Educator Award, Society of Toxicology, 2018
  • Center for Advanced Studies Excellence in Scholarship Award, U.S. Coast Guard Academy, 2017
  • Superintendent’s Award for Excellence, U.S. Coast Guard Academy, 2014

Professional Memberships

Professional Appointments

  • Adjunct Professor, 2005-present, University of Maryland World Campus, Adelphi, MD
  • Adjunct Graduate Faculty Member, 2007-present, Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Warwick, RI
  • Adjunct Assistant Professor, 2008-present, Department of Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ

Contact Information